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Table 2 Haplotype structures and frequencies in the IL-10 gene promoter

From: Association of IL-10 gene promoter polymorphisms with susceptibility to pseudoexfoliation syndrome, pseudoexfoliative and primary open-angle glaucoma

Subjects

N

GCC

ACC

GTA

ATA

GCA

PEX, n (%)

114

82 (71.9)a

16 (14)

10 (8.8)

6 (5.3)

0 (0)

Control, n (%)

126

118 (93.6)

4 (3.2)

2 (1.6)

0 (0)

2 (1.6)

p-value

 

Ref. group

0.02

0.08

0.07

0.51

OR (95% CI)

 

–

5.76 (5.17–24.49)

NA

NA

NA

PEXG, n (%)

118

86 (72.9)

22 (18.6)

8 (6.8)

2 (1.7)

0 (0)

Control, n (%)

126

118 (93.7)

4 (3.2)

2 (1.6)

0 (0)

2 (1.6)

p-value

 

Ref. group

0.006

0.16

0.42

0.51

OR (95% CI)

 

–

7.54 (6.62–30.76)

NA

NA

NA

POAG, n (%)

114

80 (70.2)

22 (19.3)

10 (8.8)

2 (1.8)

0 (0)

Control, n (%)

126

118 (93.7)

4 (3.2)

2 (1.6)

0 (0)

2 (1.6)

p-value

 

Ref. group

0.003

0.08

0.41

0.51

OR (95% CI)

 

–

8.11 (7.13–33.15)

NA

NA

NA

  1. a Numbers of haplotypes are shown with their frequencies in parentheses. Constituents of the haplotypes are written in the order of −1082 G/A, −819 C/T and – 592 C/A SNPs of IL-10
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BMC Medical Genetics

ISSN: 1471-2350

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