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Table 3 Association between FTO SNP (rs9939609) and PCOS risk under multiple models of inheritance

From: In depth analysis of the association of FTO SNP (rs9939609) with the expression of classical phenotype of PCOS: a Sri Lankan study

Model

Genotype

Controls

Cases

OR (95% CI)

p

AIC

BIC

Codominant

T/T

68 (65.4%)

20 (37%)

1.00

0.00

192.7

201.8

A/T

23 (22.1%)

13 (24.1%)

1.92 (0.83–4.47)

   

A/A

13 (12.5%)

21 (38.9%)

5.49 (2.34–12.88)

   

Dominant

T/T

68 (65.4%)

20 (37%)

1.00

0.00

195.3

201.4

A/T-A/A

36 (34.6%)

34 (63%)

3.21 (1.62–6.37)

   

Recessive

T/T-A/T

91 (87.5%)

33 (61.1%)

1.00

0.00

192.9

199

A/A

13 (12.5%)

21 (38.9%)

4.45 (2.01–9.90)

   

Overdominant

T/T-A/A

81 (77.9%)

41 (75.9%)

1.00

0.78

206.9

213

A/T

23 (22.1%)

13 (24.1%)

1.12 (0.51–2.43)

   

Logadditive

2.30 (1.51–3.51)

0.00

190.9

197

  1. OR odds ratio, CI confidence interval, AIC Akaike information criteria, BIC Bayesian information criteria