Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content

Table 5 Comparisons of clinical characteristics among genotypes rs7754840, rs7138803, and rs6548238

From: Obesity-related loci in TMEM18, CDKAL1 and FAIM2 are associated with obesity and type 2 diabetes in Chinese Han patients

 

rs7754840

P

rs7138803

P

rs6548238

CC + CG

GG

AA+AG

GG

CC + CT

TT

P

Waistcircumference (cm)

96.68 ± 17.31

90.29 ± 14.56

0.040

97.11 ± 16.42

92.53 ± 16.53

0.139

97.27 ± 16.84

90.75 ± 15.66

0.030

Waist/hip ratio

1.11 ± 0.36

0.97 ± 0.25

0.027

1.09 ± 0.30

1.04 ± 0.35

0.345

1.15 ± 0.33

0.95 ± 0.29

0.001

BMI (kg/m2)

26.48 ± 4.98

25.98 ± 5.80

0.612

27.94 ± 4.94

25.25 ± 5.25

0.006

26.94 ± 4.57

22.52 ± 5.98

0.023

FPG (mmol/L)

10.07 ± 4.00

10.14 ± 3.67

0.925

10.97 ± 3.77

9.54 ± 3.85

0.046

11.01 ± 3.80

9.01 ± 3.69

0.004

HbA1c, %

9.90 ± 3.94

9.72 ± 3.36

0.799

10.30 ± 3.74

9.53 ± 3.70

0.268

10.70 ± 4.02

8.78 ± 3.05

0.004

SBP (mm Hg)

132.91 ± 23.98

124.93 ± 17.85

0.039

130.00 (112.00,115.00)

122.00 (110.00,150.00)

0.413

131.39 ± 22.03

128.20 ± 22.39

0.432

DBP (mm Hg)

84.03 ± 11.14

82.13 ± 10.60

0.360

86.45 ± 9.91

81.34 ± 11.16

0.012

85.91 ± 9.91

80.22 ± 11.39

0.004

TG (mmol/L)

4.61 ± 4.38

4.32 ± 3.69

0.705

3.66 (1.98,7.13)

2.62 (1.42,4.84)

0.041

5.46 ± 4.80

3.36 ± 2.76

0.005

TC (mmol/L)

5.39 ± 2.60

5.38 ± 2.60

0.44

5.38 ± 2.60

4.93 ± 2.38

0.324

5.88 ± 2.45

4.51 ± 1.99

0.001

HDL-C (mmol/L)

1.05 ± 0.54

0.98 ± 0.47

0.455

0.92 (0.58,1.06)

0.97 (0.70,1.22)

0.066

0.85 ± 0.36

1.23 ± 0.59

0.001

LDL-C (mmol/L)

2.92 ± 1.01

2.37 ± 0.87

0.176

2.99 ± 0.93

2.72 ± 0.98

0.133

2.98 ± 1.04

2.63 ± 0.85

0.050

FINS (μIU/mL)

22.27 ± 17.33

17.82 ± 10.06

0.076

19.60 (16.56,26.72)

13.18 (8.72,26.10)

0.007

21.50 ± 12.51

19.55 ± 17.88

0.484

HOMA-IR

6.81 (2.98,14.05)

5.60 (3.59,13.86)

0.677

10.46 (3.72,15.07)

5.35 (2.90,12.68)

0.083

10.01 ± 8.52

8.79 ± 7.31

0.399

HOMA-IS

0.010 (0.000,0.020)

0.010 (0.005,0.017)

0.184

0.012 (0.010,0.020)

0.010 (0.000,0.020)

0.662

0.010 (0.000,0.010)

0.016 (0.010,0.020)

0.001

Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us