BMC Medical Genetics

Table 1 Characteristics of the studies included in the meta-analysis (n = 16)

From: Angiotensin-converting enzyme gene insertion/deletion polymorphism and susceptibility to psoriasis: a systematic review and meta-analysis

Genotyping
Study, year	Ethnicity	Psoriasis			Control			Source of controls	Subtype of psoriasis	Genotyping method	P-value for HWE for controls	Score^a
Study, year	Ethnicity	II	ID	DD	II	ID	DD	Source of controls	Subtype of psoriasis	Genotyping method	P-value for HWE for controls	Score^a
Vasku, 1999 [21]	Caucasian (European)	40	111	49	45	104	59	Unknown	Unknown	PCR	0.947	NA
Ozkur, 2004 [22]	Caucasian (Turkish)	12	40	34	28	69	57	Unknown	Vulgaris (94.2%)	PCR	0.378	7
Al-Awadhi, 2007 [23]	Caucasian (Arab)	7	19	25	14	45	41	Hospital- based	Arthritis	PCR	0.770	8
Chang, 2007 [24]	Asian	172	108	32	287	265	63	Hospital- based	Unknown	PCR	0.873	7
Liu, 2007 [20]	Asian	31	38	19	23	48	24	Hospital- based	Unknown	PCR	0.917	NA
Weger, 2007 [25]	Caucasian (European)	61	92	54	35	93	54	Hospital- based	Vulgaris	PCR	0.653	7
Nagui, 2012 [26]	Caucasian (Arab)	9	13	8	6	8	6	Hospital- based	Vulgaris	PCR	0.371	8
Shehab, 2008 [27]	Caucasian (Arab)	2	2	9	19	18	74	Hospital- based	Arthritis	PCR	< 0.001	6
Veletza, 2008 [28]	Caucasian (European)	2	11	14	5	7	15	Unknown	Vulgaris	PCR	0.038	7
Coto-Segura, 2009 [29]	Caucasian (European)	38	124	106	34	145	93	Population- based	Arthritis	PCR	0.050	6
Yang, 2014 [9]	Asian	350	269	49	304	299	65	Hospital- based	Unknown	PCR-RFLP	0.491	7
Munir, 2016 [30]	Caucasian (Pakistani)	118	239	129	88	299	184	Population- based	Arthritis (92%)	PCR	0.063	6
Huang, 2017 [31]	Asian	55	71	35	119	111	26	Hospital- based	Unknown	PCR	0.987	6
Agha, 2018 [32]	Caucasian (Pakistani)	72	87	74	90	122	51	Unknown	Unknown	PCR	0.405	6
Elneam, 2018 [33]	Caucasian (Arab)	18	33	22	22	17	8	Unknown	Vulgaris	PCR	0.157	7
Tanhapour, 2018 [34]	Caucasian (Iranian)	16	57	27	8	50	42	Hospital- based	Unknown	PCR-RFLP	0.191	6

Abbreviations: PCR Polymerase chain reaction; RFLP restriction fragment length polymorphism. ^aBased on the Newcastle-Ottawa Quality Assessment Scale

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