Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 5 | BMC Medical Genetics

Fig. 5

From: POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction

Fig. 5

POLE mutations regulate cellular metabolism through enhancing AMF/PGI and AMFR/gp78 expression. a The expression of AMF/PGI in endometrial cancer patients and normal samples, Normal = 35, Cancer = 551. The Y axis represents the expression of the gene (log2FPKM). b The expression of AMF/PGI in mutant and wild type POLE endometrial cancer samples, Mutant = 80, wild type = 446. The Y axis represents the expression of the gene (FPKM). c The expression of AMFR/gp78 in mutant and wild type POLE endometrial cancer samples, Mutant = 80, wild type = 446. The Y axis represents the expression of the gene (FPKM). d Kaplan–Meier curve and log-rank test for endometrial cancer patients based on the comprehensive expression of POLE and AMFR/gp78 classification

Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us