Association of vitamin D receptor TaqI and ApaI genetic polymorphisms with nephrolithiasis and end stage renal disease: a meta-analysis

Table 1 Distribution of VDR1 TaqI polymorphism in different case-control studies

Author	Year	Country	Renal disease type	Genotypes						C-allele frequency
				Cases			Control			C-allele frequency
				TT	TC	CC	TT	TC	CC	Cases	Control
Wang [23]	2016	China	ESRD	215	197	40	474	358	72	0.31	0.28
Cakir [20]	2016	Turkey	NL	35	44	19	31	29	10	0.42	0.35
Guha [13]	2015	India	NL	58	82	60	65	58	77	0.51	0.53
Martin [24]	2010	Ireland	DN	225	327	103	249	327	98	0.41	0.39
Ozkaya [16]	2003	Turkey	NL	33	27	4	50	30	10	0.27	0.28
Mossetti [25]	2003	Italy	NL	80	104	36	35	66	13	0.40	0.40
Bucan [27]	2009	Croatia	DN	5	6	3	13	14	6	0.43	0.39
Nosratabadi [7]	2010	Iran	DN	9	55	36	4	63	33	0.64	0.65
Goknar [15]	2016	Turkey	NL	25	41	12	14	43	3	0.42	0.41
Tripathi [21]	2010	India	ESRD	105	115	38	267	228	74	0.37	0.33
Mittal [22]	2010	India	NL	56	61	8	84	50	16	0.31	0.27
Moyano [26]	2007	Spain	NL	15	23	13	9	11	1	0.48	0.31
Gunes [17]	2006	Turkey	NL	37	63	10	61	73	16	0.38	0.35
Seyhan [18]	2007	Turkey	NL	27	35	18	13	25	2	0.44	0.36
Aykan [19]	2015	Turkey	NL	67	61	36	66	86	15	0.41	0.35
Han [14]	2015	China	NL	102	6	0	160	16	4	0.03	0.07

The following studies were shown to have deviation from HWE: Guha et al. (p < 0.0001), Nosratabadi et al. (p = 0.0008), Goknar et al. (p = 0.0008) and Han et al. (p = 0.0008)
ESRD end stage renal disease, NL nephrolithiasis, DN diabetic nephropathy

ISSN: 1471-2350