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Table 2 Minor allele frequencies among breast cancer patients and healthy controls and the HWEc P-value of CYP450 candidate gene polymorphisms

From: Association of CYP gene polymorphisms with breast cancer risk and prognostic factors in the Jordanian population

Gene

SNP ID

Cases (n = 221)

Controls (n = 218)

MA

MAFa

HWEb p-value

MA

MAF

HWE p-value

CYP19A1

rs7176005

T

0.23

0.85

T

0.15

0.18

rs6493497

A

0.22

0.56

A

0.15

0.18

rs700519

A

0.03

0.68

A

0.02

0.75

rs10046

A

0.42

0.27

A

0.44

0.50

rs4646

A

0.29

0.33

A

0.29

0.25

CYP2C9

rs1799853

T

0.14

0.084

T

0.15

0.063

rs4086116

T

0.22

0.17

T

0.23

0.036

CYP2C19

rs4244285

A

0.11

0.74

A

0.08

0.84

CYP1B1

rs10175368

T

0.29

0.87

T

0.26

0.16

CYP3A4

rs35599367

A

0.02

0.70

A

0.03

0.70

CYP1A2

rs762551

C

0.33

0.88

C

0.37

0.10

  1. MA minor allele
  2. N/A: not applicable
  3. aMAF: minor allele frequency
  4. bHWE: Hardy—Weinberg equilibrium
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BMC Medical Genetics

ISSN: 1471-2350

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