Table 2 Unadjusted associations between SNPs from surfactant protein A alleles (SP-A1, SP-A2) and otitis media (OM) episodes before 12 months of age for 355 infants at risk for developing asthma. (CT and MA, 1998 – 2000)
From: Association of surfactant protein A polymorphisms with otitis media in infants at risk for asthma
OM Episodes | ||
|---|---|---|
SNP | n (%) | % |
All subjects N (%) | 355 | 258 (72.7) |
SP-A1 a | ||
   aa 19 b | ||
CC | 1 (0.3) | |
CT | 56 (15.8) | 89.5 |
TT | 294 (83.8) | 69.0 |
   aa 50 | ||
CC | 75 (21.2) | 80.0 |
CG | 171 (48.3) | 69.0 |
GG | 108 (30.5) | 74.1 |
   aa 62 | ||
GG | 5 (1.4) | |
AG | 88 (25.2) | 74.2 |
AA | 256 (73.4) | 71.9 |
   aa 133 | ||
GG | 2 (0.6) | |
AG | 51 (14.4) | 83.0 |
AA | 302 (85.1) | 70.9 |
   aa 219 | ||
TT | 1 (0.3) | |
CT | 46 (13.0) | 68.1 |
CC | 308 (86.8) | 73.4 |
SP-A2 a | ||
   aa 9 | ||
CC | 73 (20.6) | 74.0 |
AC | 171 (48.2) | 71.9 |
AA | 111 (31.3) | 73.0 |
   aa 91 | ||
CC | 6 (1.7) | |
CG | 85 (24.2) | 73.6 |
GG | 261 (74.2) | 72.4 |
   aa 140 | ||
TT | 25 (7.1) | 64.0 |
CT | 142 (40.2) | 71.1 |
CC | 186 (52.7) | 75.3 |
   aa 223 | ||
AA | 18 (5.1) | 77.8 |
AC | 129 (36.3) | 72.9 |
CC | 208 (58.6) | 72.1 |