Table 4 Haplotypes of A>G (-6) – Thr174Met – Met235Thr SNPs in AGT gene tested for association with diabetic chronic renal insufficiency.
Haplotype* | DM | CRI | χ2 | P (df = 2) | O.R. (95%CI) | ||
|---|---|---|---|---|---|---|---|
n | Freq. | n | Freq. | ||||
A-C-T | 92 | 0.236 | 23 | 0.06 | 47.38 | 0.0000** | 0.260 (1.27–0.33) |
A-C-C | 93 | 0.24 | 174 | 0.45 | 16.99 | 0.0000** | 1.93 (1.41–2.65) |
A-T-T | 08 | 0.20 | 01 | 0.003 | 5.4 | 0.02 | 0.125 (0.015–1.00) |
A-T-C | 16 | 0.04 | 30 | 0.08 | 4.76 | 0.029 | 1.98 (1.06–3.69) |
G-C-T | 144 | 0.37 | 118 | 0.31 | 3.32 | 0.068 | 0.758 (0.56–1.02) |
G-C-C | 25 | 0.06 | 25 | 0.065 | 0.06 | 0.81 | 0.93 (0.52–1.67) |
G-T-T | 06 | 0.015 | 01 | 0.003 | 3.526 | 0.06 | 0.167 (0.02–1.39) |
G-T-C | 06 | 0.015 | 14 | 0.036 | 3.14 | 0.076 | 2.34 (0.89–6.15) |