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Table 2 Comparison of MMP9 haplotype frequency estimates in cases and controls and risk estimates from CLR analysis of matched case-control pairs. The haplotype configuration is as follows: Q279R, R574P, G607G and V694V.

From: A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatisinfection

haplotype

# controls

freq

# cases (TS)

freq

p-value

CLR:OR (95%CI)

# controls

freq

# cases(TT)

freq

p-value

CLR:OR (95%CI)

ACCG

450

0.34

466

0.36

-

reference

204

0.32

218

0.36

-

reference

ACAG

298

0.22

303

0.23

0.845

0.98(0.80, 1.21)

150

0.24

167

0.27

0.514

1.11 (0.82, 1.50)

GCAA

201

0.15

186

0.14

0.257

0.87 (0.69, 1.11)

91

0.14

75

0.12

0.224

0.79 (0.54, 1.15)

GCAG

161

0.12

130

0.10

0.048

0.77 (0.59, 0.99)

80

0.13

55

0.09

0.021

0.62 (0.41, 0.93)

AGAG

123

0.09

130

0.10

0.705

1.06 (0.79,1.40)

61

0.10

55

0.09

0.451

0.85 (0.56, 1.30)

AGCG

66

0.05

55

0.04

0.204

0.78 (0.53, 1.15)

33

0.05

27

0.04

0.171

0.66 (0.37, 1.20)

GCCG

30

0.02

32

0.02

0.977

0.99 (0.58, 1.68)

13

0.02

17

0.03

0.604

1.24 (0.56, 2.75)

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BMC Medical Genetics

ISSN: 1471-2350

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