Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations

Table 2 Genes with decreased levels of expression in at least 3 of 4 mutant MeCP2 expressing clonal fibroblast cell strains when compared to matched clonal wild type MeCP2 expressing cell strains

GenBank Accession	Expression In Brain	Gene Symbol/UniGene No.	Gene Name	Function
AC003107		COMP	Cartilage oligomeric matrix protein	extracellular matrix protein
L32137		COMP	Cartilage oligomeric matrix protein	extracellular matrix protein
U59289	x	CDH13	Cadherin 13, H-cadherin	cell adhesion
X53586	x	ITGA6	Integrin, alpha 6	cell adhesion
AI815057		KLF5	Kruppel-like factor 5	transcriptional regulation of cellular proliferation
D43969	x	RUNX1	Runt-related transcription factor 1	transcription factor
L27560	x	IGFBP5	insulin-like growth factor binding protein 5	growth homeostasis
AW022852	x	IGFBP5	insulin-like growth factor binding protein 5	growth homeostasis
AI433710	x	Hs.25557	plasma-cell membrane glycoprotein PC-1^a	nucleotide phosphatase
AA142891	x	P4HA2	prolyl 4-hydroxylase (alpha subunit)^a	hydroxylase
U38810	x	MAB21L1	Mab-21-like	eye and cerebellum development
Y00815	x	PTPRF	protein tyrosine phosphatase, receptor type, F	cell signaling
AI017574	x	CRIP1	Cysteine-rich protein 1	zinc carrier protein
AI862775	x	Hs.66915	sphingolipid G-protein-coupled receptor, 5^a	endothelial differentiation
AL035494		Hs.184736
AI125670	x	Hs.16346
AI718385	x	Hs.302738
AI818579		Hs.121520
AI597757		Hs.207407
AI935827		Hs.169758
AB018289		Hs.49500

ISSN: 1471-2350