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Table 1 Clinical characteristics of study subjects

From: The G-308A variant of the Tumor Necrosis Factor-α (TNF-α) gene is not associated with obesity, insulin resistance and body fat distribution

 

Obese subjects

Lean subjects

p-value

 

(n = 115)

(n = 79)

 

Age (yrs)

47.04 ± 1.3

51.36 ± 1.8

P < 0.01

Sex (M/F)

37 / 78

27/52

NS

BMI (kg/m2)

33.93 ± 0.512

24.30 ± 0.313

<0.0001

Blood glucose (mg/dl)

91.56 ± 2.0

86.84 ± 10.08

NS

Fasting plasma insulin (μU/ml)

22.72 ± 1.7

9.29 ± 1.04

<0.0001

HOMAIR

5 ± 0.16

2.2 ± 0.45

<0.0003

Plasma lipids (mg/dL)

   

   Total cholesterol

218.69 ± 4.5

214.95 ± 6.1

NS

   HDL cholesterol.

48.16 ± 1.4

48.2 ± 2.2

NS

   Total triglycerides

156.85 ± 12.5

157.26 ± 12.96

NS

   LDL cholesterol

128.61 ± 5.1

131.2 ± 5

NS

  1. Data are given as means ± SEM. All p-values were corrected for differences in age The statistical analysis of total triglycerides and plasma insulin were performed on log-trasformed values, but the untrasformed values are given in table. Continuous variables were compared by t-test and categorical variables by Χ2 test.
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BMC Medical Genetics

ISSN: 1471-2350

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